Back to Search
Start Over
Community-associated meticillin-resistant Staphylococcus aureus carriage in hospitalized patients in tropical northern Australia.
- Source :
-
The Journal of hospital infection [J Hosp Infect] 2013 Mar; Vol. 83 (3), pp. 205-11. Date of Electronic Publication: 2013 Jan 15. - Publication Year :
- 2013
-
Abstract
- Background: Community-associated meticillin-resistant Staphylococcus aureus (CA-MRSA) was first reported in remote Australian Aboriginal communities. It is a prominent clinical pathogen in northern Australia with potential for transmission within the local hospital setting.<br />Aim: To determine epidemiological characteristics of S. aureus carriage within the Royal Darwin Hospital.<br />Methods: We screened two patient groups: an 'admission group' recruited within 48 h of admission; and an 'inpatient group' recruited five or more days after admission. S. aureus isolates were characterized by antibiotic susceptibility testing and genotyped by a multi-locus sequence type-based high-resolution melting scheme.<br />Findings: S. aureus carriage on admission was 30.7% of 225 compared with 34.8% among 201 inpatients, with MRSA carriage of 2.2% and 18.9% respectively. We isolated CA-MRSA from 0.9% and 10.4%, and healthcare-associated (HCA)-MRSA from 1.3% and 9.0% of the admission and inpatient groups, respectively. Among the inpatient group, hospital-associated ST239 was the most common MRSA strain. CA-MRSA was represented by one clonal complex (CC) in the admission group (CC5) and seven CCs in the inpatient group (CC1, 93, 5, 6, 30, 75, 88).<br />Conclusion: Inpatient carriage of multiple CA-MRSA lineages suggests selection for and transmission within the hospital of not only typical HCA-MRSA, but also diverse CA-MRSA strains.<br /> (Copyright © 2012 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.)
- Subjects :
- Adult
Anti-Bacterial Agents pharmacology
Australia epidemiology
Carrier State microbiology
Community-Acquired Infections microbiology
Cross-Sectional Studies
Female
Humans
Male
Microbial Sensitivity Tests
Middle Aged
Prevalence
Staphylococcal Infections microbiology
Carrier State epidemiology
Community-Acquired Infections epidemiology
Methicillin-Resistant Staphylococcus aureus isolation & purification
Staphylococcal Infections epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 1532-2939
- Volume :
- 83
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- The Journal of hospital infection
- Publication Type :
- Academic Journal
- Accession number :
- 23332351
- Full Text :
- https://doi.org/10.1016/j.jhin.2012.10.014