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Histoplasmosis and subcutaneous nodules in a kidney transplant recipient: erythema nodosum versus fungal panniculitis.
- Source :
-
Transplant infectious disease : an official journal of the Transplantation Society [Transpl Infect Dis] 2013 Apr; Vol. 15 (2), pp. E58-63. Date of Electronic Publication: 2013 Jan 20. - Publication Year :
- 2013
-
Abstract
- Erythema nodosum (EN)-like lesions are a rare occurrence after solid organ transplantation. Differential diagnosis includes infective panniculitis, which can be a feature of progressive disseminated histoplasmosis (PDH), an uncommon but severe form affecting primarily immunocompromised hosts. We report on a fatal case of PDH, which presented as fungal panniculitis masquerading as EN in a renal allograft recipient 25 years after transplantation. We discuss the clinical, histopathological, and microbiological characteristics of this rare complication, with focus on its distinction from EN. This case emphasizes the central role of biopsy in transplant recipients presenting with cutaneous lesions, and the importance of clinicopathologic correlation and complementary microbiological investigations.<br /> (© 2013 John Wiley & Sons A/S.)
- Subjects :
- Anti-Bacterial Agents therapeutic use
Diagnosis, Differential
Erythema Nodosum drug therapy
Erythema Nodosum microbiology
Fatal Outcome
Female
Humans
Middle Aged
Panniculitis drug therapy
Panniculitis microbiology
Time Factors
Erythema Nodosum diagnosis
Histoplasma isolation & purification
Histoplasmosis etiology
Kidney Transplantation
Panniculitis diagnosis
Subjects
Details
- Language :
- English
- ISSN :
- 1399-3062
- Volume :
- 15
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Transplant infectious disease : an official journal of the Transplantation Society
- Publication Type :
- Academic Journal
- Accession number :
- 23331504
- Full Text :
- https://doi.org/10.1111/tid.12052