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Asymptomatic primary tuberculous pleurisy with intense 18-fluorodeoxyglucose uptake mimicking malignant mesothelioma.
- Source :
-
BMC infectious diseases [BMC Infect Dis] 2013 Jan 14; Vol. 13, pp. 12. Date of Electronic Publication: 2013 Jan 14. - Publication Year :
- 2013
-
Abstract
- Background: The pathogenesis of primary tuberculous pleurisy is a delayed-type hypersensitivity immunogenic reaction to a few mycobacterial antigens entering the pleural space rather than direct tissue destruction by mycobacterial proliferation. Although it has been shown that pulmonary tuberculosis induces 18-fluorodeoxyglucose (FDG) uptake in active lesions, little is known about the application of FDG positron emission/computed tomography (FDG PET/CT) to the management of primary tuberculous pleurisy.<br />Case Presentation: We report a case of asymptomatic primary tuberculous pleurisy presenting with diffuse nodular pleural thickening without distinct pleural effusion and parenchymal lung lesions mimicking malignant mesothelioma. An initial FDG PET/CT scan demonstrated multiple lesions of intense FDG uptake in the right pleura and thoracoscopic biopsy of pleural tissue revealed caseous granulomatous inflammation. The patient received antituberculous therapy for 6 months, with clearly decreased positive signals on a repeated FDG PET/CT scan.<br />Conclusion: FDG PET/CT imaging may be useful for evaluating disease activity in tuberculous pleurisy patients with an unknown time of onset.
- Subjects :
- Adult
Biopsy
Diagnosis, Differential
Humans
Male
Pleura pathology
Thoracoscopy
Tuberculosis, Pleural drug therapy
Fluorodeoxyglucose F18
Mesothelioma diagnosis
Multimodal Imaging
Pleural Neoplasms diagnosis
Positron-Emission Tomography
Tomography, X-Ray Computed
Tuberculosis, Pleural diagnosis
Subjects
Details
- Language :
- English
- ISSN :
- 1471-2334
- Volume :
- 13
- Database :
- MEDLINE
- Journal :
- BMC infectious diseases
- Publication Type :
- Academic Journal
- Accession number :
- 23317113
- Full Text :
- https://doi.org/10.1186/1471-2334-13-12