Back to Search
Start Over
Results of transoral laser microsurgery for supraglottic carcinoma in 277 patients.
- Source :
-
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery [Eur Arch Otorhinolaryngol] 2013 Aug; Vol. 270 (8), pp. 2315-26. Date of Electronic Publication: 2013 Jan 10. - Publication Year :
- 2013
-
Abstract
- The objective of the study was to evaluate the oncological and functional results of transoral laser microsurgery (TLM) in patients with supraglottic laryngeal squamous cell carcinoma. Between June 1980 and December 2006, 277 patients with squamous cell supraglottic carcinoma of all stages were treated by primary carbon dioxide laser microsurgery. All treatments were performed with curative intention. The goal was the complete tumor removal with preservation of functionally important structures of the larynx. The administered treatment was exclusively TLM with or without selective or modified radical neck dissection in 215 cases (78 %); TLM with postoperative radiotherapy was performed in 62 cases (22 %). Data were analyzed using the Kaplan-Meier method. The median follow-up was 65 months. We achieved a 5-year local control rate of 85% for pT1/pT2, 82% for pT3, and 76% for pT4. The 5-year overall, recurrence-free and disease-specific survival rates for stages I and II were 76, 81, and 92%, for stages III and IVa 59, 65, and 81%, respectively. With respect to local control and survival, these results are comparable with the results achieved by conventional partial and total resection of the larynx, while being superior to primary (chemo)radiotherapy. Transoral laser microsurgery results in a low morbidity, rapid recovery, and superior function compared with standard therapy.
- Subjects :
- Adult
Aged
Aged, 80 and over
Carcinoma, Squamous Cell mortality
Carcinoma, Squamous Cell radiotherapy
Combined Modality Therapy
Female
Humans
Kaplan-Meier Estimate
Laryngeal Neoplasms mortality
Laryngeal Neoplasms radiotherapy
Male
Middle Aged
Neck Dissection
Neoplasm Recurrence, Local
Neoplasm Staging
Survival Rate
Treatment Outcome
Carcinoma, Squamous Cell surgery
Laryngeal Neoplasms surgery
Laser Therapy methods
Microsurgery methods
Subjects
Details
- Language :
- English
- ISSN :
- 1434-4726
- Volume :
- 270
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
- Publication Type :
- Academic Journal
- Accession number :
- 23306348
- Full Text :
- https://doi.org/10.1007/s00405-012-2327-6