Fever and psychosis as an early presentation of Brucella-associated meningoencephalitis: a case report.

Authors :: Montazeri M
Sadeghi K
Khalili H
Davoudi S
Source :: Medical principles and practice : international journal of the Kuwait University, Health Science Centre [Med Princ Pract] 2013; Vol. 22 (5), pp. 506-9. Date of Electronic Publication: 2013 Jan 05.
Publication Year :: 2013
Abstract: Objective: To describe a case with Brucella-associated meningoencephalitis. In addition, we report drug-induced hepatotoxicity due to acyclovir.<br />Clinical Presentation and Intervention: A young woman was admitted with fever and psychosis and neuroimaging findings indicative of meningoencephalitis. Serology was positive for Brucella. She was treated with doxycycline, rifampin, and trimethoprim-sulfamethoxazole.<br />Conclusion: This case reminds physicians in endemic regions to consider neurobrucellosis as a differential diagnosis in patients with any unexplained neurologic symptoms or atypical psychosis. Early diagnosis and treatment of neurobrucellosis will be helpful in decreasing the sequelae of this complication.<br /> (Copyright © 2013 S. Karger AG, Basel.)

Subjects :: Acyclovir adverse effects
Adult
Anti-Bacterial Agents
Brain
Chemical and Drug Induced Liver Injury
Drug Therapy, Combination
Female
Humans
Organic Chemicals
Brucella
Fever etiology
Meningoencephalitis complications
Meningoencephalitis microbiology
Psychotic Disorders etiology

Language :: English
ISSN :: 1423-0151
Volume :: 22
Issue :: 5
Database :: MEDLINE
Journal :: Medical principles and practice : international journal of the Kuwait University, Health Science Centre
Publication Type :: Academic Journal
Accession number :: 23295541
Full Text :: https://doi.org/10.1159/000345640

Full Text Access

Tools