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Burdock fermented by Aspergillus awamori elevates cecal Bifidobacterium, and reduces fecal deoxycholic acid and adipose tissue weight in rats fed a high-fat diet.
- Source :
-
Bioscience, biotechnology, and biochemistry [Biosci Biotechnol Biochem] 2013; Vol. 77 (1), pp. 53-7. Date of Electronic Publication: 2013 Jan 07. - Publication Year :
- 2013
-
Abstract
- This study investigated the effects of dietary supplementation with burdock powder and Aspergillus awamori-fermented burdock powder at 5% on the intestinal luminal environment and body fat in rats fed a high-fat (HF) diet. Food intake and growth were unaffected by dietary manipulation. Consumption of the burdock and fermented burdock diets significantly elevated fecal IgA and mucins (indices of intestinal immune and barrier functions) and reduced fecal lithocholic acid (a risk factor for colon cancer) (p<0.05). The fermented burdock diet markedly elevated cecal Bifidobacterium and organic acids, including lactate, acetate, propionate, and butyrate, and reduced fecal deoxycholic acid (a risk factor for colon cancer) and perirenal adipose tissue weight (p<0.05), but the burdock diet did not. These results suggest that consumption of fermented burdock improves the intestinal luminal environment and suppresses obesity in rats fed a HF diet.
- Subjects :
- Acetic Acid metabolism
Adipose Tissue metabolism
Animals
Bifidobacterium growth & development
Bifidobacterium metabolism
Butyric Acid metabolism
Cecum microbiology
Deoxycholic Acid metabolism
Diet, High-Fat adverse effects
Dietary Supplements
Eating drug effects
Feces chemistry
Fermentation
Immunoglobulin A metabolism
Lactic Acid metabolism
Male
Mucins metabolism
Obesity etiology
Obesity metabolism
Propionates metabolism
Rats
Rats, Sprague-Dawley
Adipose Tissue drug effects
Arctium chemistry
Aspergillus metabolism
Cecum chemistry
Obesity prevention & control
Powders administration & dosage
Subjects
Details
- Language :
- English
- ISSN :
- 1347-6947
- Volume :
- 77
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Bioscience, biotechnology, and biochemistry
- Publication Type :
- Academic Journal
- Accession number :
- 23291748
- Full Text :
- https://doi.org/10.1271/bbb.120551