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Non-alcoholic fatty liver disease is associated with cardiovascular risk factors of metabolic syndrome.
- Source :
-
Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi [Rev Med Chir Soc Med Nat Iasi] 2012 Jul-Sep; Vol. 116 (3), pp. 692-9. - Publication Year :
- 2012
-
Abstract
- Aim: To evaluate the prevalence of steatosis and to assess its correlations with the classical cardiovascular (CV) risk factors, components of metabolic syndrome (MS) in a rural population.<br />Material and Methods: A sample of 254 subjects was enrolled in the study. Collected data included: age, gender, complete medical history, anthropometric and blood pressure (BP) measurements. The biological evaluation included metabolic and hepatic parameters. Ultrasound evaluation of steatosis relied on the criteria of the National Health and Nutrition Examination Survey (NHANES) III.<br />Results: Two thirds of the study population were obese or overweight (64.96%); 32.66% had systolic BP and 27.16% diastolic BP levels higher than normal. 38% of the subjects had abnormal fasting blood glucose levels, 14.56% having glycated hemoglobin (HbA1c) values corresponding to pre-diabetes, and 9.84% to overt diabetes; 8% had low HDL-cholesterol and 14.96% high triglycerides (Tg) levels. MS was present in 50.8% of individuals. Only 10.8% of all subjects did not have an ultrasound appearance of steatosis; 28.8% had moderate and 32% severe steatosis. There were statistically significant differences in subjects with steatosis vs. subjects without steatosis with regard to body mass index (BMI), WC, presence of MS, and BP and Tg levels, but not to ALAT, ASAT and GGT values.<br />Conclusions: The important prevalence of obesity, fasting hyperglycamia, steatosis and MS shows a particularly metabolic fragile population; early diagnosis and interventional strategies are mandatory.
- Subjects :
- Adult
Aged
Biomarkers blood
Blood Pressure Determination
Body Mass Index
Cardiovascular Diseases blood
Cardiovascular Diseases epidemiology
Cardiovascular Diseases etiology
Cardiovascular Diseases physiopathology
Cholesterol, HDL blood
Cross-Sectional Studies
Early Diagnosis
Fatty Liver blood
Fatty Liver epidemiology
Fatty Liver physiopathology
Female
Glucose Tolerance Test methods
Glycated Hemoglobin metabolism
Humans
Male
Metabolic Syndrome blood
Metabolic Syndrome epidemiology
Metabolic Syndrome physiopathology
Middle Aged
Non-alcoholic Fatty Liver Disease
Obesity blood
Obesity epidemiology
Obesity physiopathology
Overweight complications
Prevalence
Risk Assessment
Risk Factors
Romania epidemiology
Rural Population statistics & numerical data
Sampling Studies
Triglycerides blood
Cardiovascular Diseases complications
Fatty Liver complications
Metabolic Syndrome complications
Obesity complications
Subjects
Details
- Language :
- English
- ISSN :
- 0048-7848
- Volume :
- 116
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi
- Publication Type :
- Academic Journal
- Accession number :
- 23272512