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Liver transplantation from hepatitis B surface antigen-positive donors.
- Source :
-
Transplantation proceedings [Transplant Proc] 2013 Jan-Feb; Vol. 45 (1), pp. 279-80. Date of Electronic Publication: 2012 Sep 18. - Publication Year :
- 2013
-
Abstract
- One possibility to increase the organ pool is to use grafts from hepatitis B virus (HBV) surface antigen (HBsAg)-positive donors, but few data are currently available in this setting. Herein, we reviewed the outcome of 92 liver transplantations using allografts from HBsAg-positive donors in the United States (1990-2009). They had experienced HBV-related (n = 68) or HBV-unrelated disease (n = 24). There was no difference between patients who received HBsAg-positive versus HBsAg-negative allografts based on age, Model for End-stage Liver Disease (MELD) score, length of stay, wait time, and donor risk index. HBsAg-positive allografts were more likely to be imported and used in MELD exceptional cases. Allograft and patient survival were comparable between the two groups. HBsAg-positive allografts deserve consideration when no other organ is available in a suitable waiting time in the present era of highly effective antiviral therapy.<br /> (Copyright © 2013 Elsevier Inc. All rights reserved.)
- Subjects :
- Databases, Factual
Graft Survival
Hepatitis B Antibodies immunology
Hepatitis B virus
Humans
Middle Aged
Risk Factors
Transplantation, Homologous
United States
Donor Selection
End Stage Liver Disease surgery
Hepatitis B therapy
Hepatitis B Surface Antigens immunology
Liver Transplantation methods
Tissue Donors
Subjects
Details
- Language :
- English
- ISSN :
- 1873-2623
- Volume :
- 45
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Transplantation proceedings
- Publication Type :
- Academic Journal
- Accession number :
- 23267801
- Full Text :
- https://doi.org/10.1016/j.transproceed.2012.05.077