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The osteocalcin gene rs1800247 polymorphism in Kashubian population.

The osteocalcin gene rs1800247 polymorphism in Kashubian population.

Authors :
Specjalski K
Porzezińska M
Siemińska A
Słomiński JM
Jassem E
Source :
Rheumatology international [Rheumatol Int] 2013 Dec; Vol. 33 (12), pp. 3043-4. Date of Electronic Publication: 2012 Dec 12.
Publication Year :
2013

Abstract

Osteocalcin is the most important noncollagenous protein component of the bone. Polymorphisms of osteocalcin gene were reported to be associated with bone mineral density. However, this relation was only confirmed in some populations. In this study presence of C/T polymorphism in osteocalcin gene (rs1800247) was determined in Kashubian population (northern Poland). The frequencies of variants were CC 9 %, TC 31 %, and TT 60 %, with no significant differences between genders. The genotypes were in Hardy-Weinberg equilibrium.

Details

Language :
English
ISSN :
1437-160X
Volume :
33
Issue :
12
Database :
MEDLINE
Journal :
Rheumatology international
Publication Type :
Academic Journal
Accession number :
23233116
Full Text :
https://doi.org/10.1007/s00296-012-2575-1