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The osteocalcin gene rs1800247 polymorphism in Kashubian population.
The osteocalcin gene rs1800247 polymorphism in Kashubian population.
- Source :
-
Rheumatology international [Rheumatol Int] 2013 Dec; Vol. 33 (12), pp. 3043-4. Date of Electronic Publication: 2012 Dec 12. - Publication Year :
- 2013
-
Abstract
- Osteocalcin is the most important noncollagenous protein component of the bone. Polymorphisms of osteocalcin gene were reported to be associated with bone mineral density. However, this relation was only confirmed in some populations. In this study presence of C/T polymorphism in osteocalcin gene (rs1800247) was determined in Kashubian population (northern Poland). The frequencies of variants were CC 9 %, TC 31 %, and TT 60 %, with no significant differences between genders. The genotypes were in Hardy-Weinberg equilibrium.
Details
- Language :
- English
- ISSN :
- 1437-160X
- Volume :
- 33
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- Rheumatology international
- Publication Type :
- Academic Journal
- Accession number :
- 23233116
- Full Text :
- https://doi.org/10.1007/s00296-012-2575-1