How many sputum culture results do we need to monitor multidrug-resistant-tuberculosis (MDR-TB) patients during treatment?

Authors :: Janssen S
Padanilam X
Louw R
Mahanyele R
Coetzee G
Hänscheid T
Leenstra T
Grobusch MP
Source :: Journal of clinical microbiology [J Clin Microbiol] 2013 Feb; Vol. 51 (2), pp. 644-6. Date of Electronic Publication: 2012 Dec 05.
Publication Year :: 2013
Abstract: Discharge of a hospital patient after a single negative sputum culture may save money when treating multidrug-resistant tuberculosis. However, after initial sputum conversion in 336 South Africans, 11.6% and 5.4% reconverted after 1 and 2 months, respectively. These findings endorse the WHO definitions of 2 negative cultures taken ≥ 30 days apart after sputum culture conversion.

Subjects :: Adult
Antitubercular Agents pharmacology
Antitubercular Agents therapeutic use
Female
Follow-Up Studies
Humans
Male
Microbial Sensitivity Tests
Middle Aged
Time Factors
Tuberculosis, Multidrug-Resistant drug therapy
Mycobacterium tuberculosis drug effects
Mycobacterium tuberculosis growth & development
Mycobacterium tuberculosis isolation & purification
Sputum microbiology
Tuberculosis, Multidrug-Resistant diagnosis

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