Spread of different rhinovirus B genotypes in hospitalized children in Spain.

Authors :: Cuevas MT
Molinero M
Pozo F
Calvo C
García-García ML
Reyes N
Ledesma J
Casas I
Source :: Influenza and other respiratory viruses [Influenza Other Respir Viruses] 2013 Sep; Vol. 7 (5), pp. 623-8. Date of Electronic Publication: 2012 Dec 06.
Publication Year :: 2013
Abstract: Human Rhinovirus (HRV) classification is an evolving process. New genotypes have been described within HRV-A and HRV-C species, but only one has been accepted related to HRV-B. From 2003 to 2010, a total of 3987 nasopharyngeal aspirate samples were taken from pediatric patients admitted to the Severo Ochoa Hospital in Madrid (Spain). After viral analysis, 949 (23.8%) tested positive to HRV. A random selection of 397 (42%) positive samples showed that 39 (9.8%) were HRV-B. The sequencing of partial VP4/VP2 coding region revealed the spread of 13 of 25 defined HRV-B serotypes and three putative new genotypes. Such results remark the high diversity of HRV-B.<br /> (© 2012 John Wiley & Sons Ltd.)