Structure and stability of hexadentate complexes of ligands based on AAZTA for efficient PET labelling with gallium-68.

Authors :: Waldron BP
Parker D
Burchardt C
Yufit DS
Zimny M
Roesch F
Source :: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2013 Jan 21; Vol. 49 (6), pp. 579-81. Date of Electronic Publication: 2012 Dec 04.
Publication Year :: 2013
Abstract: Pre-organised tricarboxylate ligands based on 6-amino-perhydro-1,4-diazepine bind (68)Ga rapidly and selectively in acetate buffer at pH 4 to 7, forming kinetically stable complexes suitable for use in PET imaging.

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