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Meeting report: international workshop on endocrine disruptors: exposure and potential impact on consumers health.

Authors :
Rousselle C
Ormsby JN
Schaefer B
Lampen A
Platzek T
Hirsch-Ernst K
Warholm M
Oskarsson A
Nielsen PJ
Holmer ML
Emond C
Source :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2013 Feb; Vol. 65 (1), pp. 7-11. Date of Electronic Publication: 2012 Dec 02.
Publication Year :
2013

Abstract

The French Agency for Food, Environmental and Occupational Health and Safety (Anses) hosted a two-day workshop on Endocrine Disruptors: Exposure and Potential Impact on Consumers Health, bringing together participants from international organizations, academia, research institutes and from German, Swedish, Danish and French governmental agencies. The main objective of the workshop was to share knowledge and experiences on endocrine disruptors (ED) exposure and potential impact on consumers' health, to identify current risk assessment practices and knowledge gaps and issue recommendations on research needs and future collaboration. The following topics were reviewed: (1) Definition of ED, (2) endpoints to be considered for Risk assessment (RA) of ED, (3) non-monotonic dose response curves, (4) studies to be considered for RA (regulatory versus academic studies), (5) point of departure and uncertainty factors, (6) exposure assessment, (7) regulatory issues related to ED. The opinions expressed during this workshop reflect day-to-day experiences from scientists, regulators, researchers, and others from many different countries in the fields of risk assessment, and were regarded by the attendees as an important basis for further discussions. Accordingly, the participants underlined the need for more exchange in the future to share experiences and improve the methodology related to risk assessment for endocrine disrupters.<br /> (Copyright © 2012 Elsevier Inc. All rights reserved.)

Details

Language :
English
ISSN :
1096-0295
Volume :
65
Issue :
1
Database :
MEDLINE
Journal :
Regulatory toxicology and pharmacology : RTP
Accession number :
23211416
Full Text :
https://doi.org/10.1016/j.yrtph.2012.11.010