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Outcome of match related allogeneic stem cell transplantation procedures performed from 2004 till 2011.

Authors :
Ali N
Adil SN
Shaikh MU
Moosajee M
Masood N
Source :
Experimental hematology & oncology [Exp Hematol Oncol] 2012 May 18; Vol. 1 (1), pp. 13. Date of Electronic Publication: 2012 May 18.
Publication Year :
2012

Abstract

We present our initial experience of allogeneic stem cell transplant procedure performed between April 2004 and August 2011 for various haematological disorders. All patients with non-malignant and malignant haematological disorders with HLA matched donors were selected after pre-transplant workup. Ninety seven patients underwent the procedure. Most common indications for transplant were aplastic anaemia in n = 34 (35%), followed by β-Thalassemia major in n = 21 (21.6%) and chronic myeloid leukemia in n = 11 patients (11.3%). Primary graft failure present was present in 2.06%. Incidence of graft versus host disease (GvHD) in our patients was 34%. After median follow-up of five years the overall survival was 71.3% with a mean survival time of 51.2 ± 3.3 months.

Details

Language :
English
ISSN :
2162-3619
Volume :
1
Issue :
1
Database :
MEDLINE
Journal :
Experimental hematology & oncology
Publication Type :
Academic Journal
Accession number :
23210643
Full Text :
https://doi.org/10.1186/2162-3619-1-13