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A novel ratiometric emission probe for Ca2+ in living cells.
- Source :
-
Organic & biomolecular chemistry [Org Biomol Chem] 2013 Jan 21; Vol. 11 (3), pp. 503-8. Date of Electronic Publication: 2012 Nov 30. - Publication Year :
- 2013
-
Abstract
- A ratiometric fluorescent probe for Ca(2+) based on 1,3,4-oxadiazole derivative has been designed and developed. The probe exhibits a large Stokes shift of 202 nm and a highly selective ratiometric emission response (490/582 nm) to Ca(2+) over other metal cations. Additionally, the probe can readily reveal the changes of intracellular Ca(2+) concentration in living human umbilical vein endothelial cells.
Details
- Language :
- English
- ISSN :
- 1477-0539
- Volume :
- 11
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Organic & biomolecular chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 23202385
- Full Text :
- https://doi.org/10.1039/c2ob26888d