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Prevalence of transmitted HIV-1 drug resistance mutations in children and adolescents in São Paulo, Brazil.
- Source :
-
The Pediatric infectious disease journal [Pediatr Infect Dis J] 2012 Dec; Vol. 31 (12), pp. e255-7. - Publication Year :
- 2012
-
Abstract
- HIV drug resistance genotype testing, performed on 39 HIV-infected treatment-naive children from 2000 to 2011, identified 5 children (12.8%) with drug resistance mutations: 5.3% to nucleoside reverse transcriptase inhibitors, 5.3% to nonnucleoside reverse transcriptase inhibitors and 7.7% to protease inhibitors. There was a trend for increasing prevalence of drug resistance mutations during the 11-year study period.
- Subjects :
- Adolescent
Brazil epidemiology
Child
Child, Preschool
Female
Genotype
HIV Infections epidemiology
HIV-1 genetics
HIV-1 isolation & purification
Humans
Infant
Infant, Newborn
Male
Prevalence
Drug Resistance, Viral
HIV Infections transmission
HIV Infections virology
HIV-1 drug effects
Mutation, Missense
Subjects
Details
- Language :
- English
- ISSN :
- 1532-0987
- Volume :
- 31
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- The Pediatric infectious disease journal
- Publication Type :
- Academic Journal
- Accession number :
- 23188105
- Full Text :
- https://doi.org/10.1097/INF.0b013e3182684d8e