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Changes in activities of daily living, nutrient intake, and systemic inflammation in elderly adults receiving recuperative care.
- Source :
-
Journal of the American Geriatrics Society [J Am Geriatr Soc] 2012 Dec; Vol. 60 (12), pp. 2246-53. Date of Electronic Publication: 2012 Nov 23. - Publication Year :
- 2012
-
Abstract
- Objectives: To determine the relationships between physical function, systemic inflammation, and nutrient intake in elderly adults who are deconditioned or recovering from medical illness.<br />Design: Prospective observational study.<br />Setting: Recuperative care and rehabilitation setting of a Veterans Affairs hospital.<br />Participants: Older adults assessed to be in need of and likely to benefit from specialized inpatient care (N = 336, aged 78.9 ± 7.5, median length of stay 24 days).<br />Measurements: Functional assessments and plasma analyses for albumins and inflammatory markers were performed at admission and discharge. Complete nutrient intake assessments were performed daily. Katz (independence in activities of daily living) and walking endurance (distance capability and summation of need for assistive device and human help) scores were based on direct observation and provider query. Data were analyzed using least-squares and logistic regression analyses.<br />Results: Changes in physical function between admission and discharge were positively correlated with change in nutrient intake and inversely correlated with inflammation at admission and its change. Participants in the upper quartile of change for nutrient intake (particularly improved protein intake) were two to three times as likely to experience a clinically significant change in functional status during the hospitalization. Similarly, the odds of experiencing an improvement in physical function were two to four times as great for participants whose C-reactive protein levels declined as for those whose levels increased. These relationships remained significant after controlling for age, length of stay, and other baseline indicators of health status.<br />Conclusion: Protein intake and inflammation are significantly correlated with functional recovery for aging individuals undergoing recuperative care and rehabilitation. Future studies should investigate whether combined interventions that target these factors improve recovery during hospitalization for this population.<br /> (© 2012, Copyright the Authors Journal compilation © 2012, The American Geriatrics Society.)
- Subjects :
- Aged
Aged, 80 and over
C-Reactive Protein
Female
Geriatric Assessment
Humans
Interleukin-6 blood
Male
Prealbumin analysis
Serum Albumin analysis
Tumor Necrosis Factor-alpha blood
Walking
Activities of Daily Living
Dietary Proteins administration & dosage
Energy Intake
Hospital Units
Inflammation diagnosis
Physical Endurance
Recovery of Function
Rehabilitation Centers
Subjects
Details
- Language :
- English
- ISSN :
- 1532-5415
- Volume :
- 60
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- Journal of the American Geriatrics Society
- Publication Type :
- Academic Journal
- Accession number :
- 23176675
- Full Text :
- https://doi.org/10.1111/jgs.12007