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Glucose-neopentyl glycol (GNG) amphiphiles for membrane protein study.

Authors :
Chae PS
Rana RR
Gotfryd K
Rasmussen SG
Kruse AC
Cho KH
Capaldi S
Carlsson E
Kobilka B
Loland CJ
Gether U
Banerjee S
Byrne B
Lee JK
Gellman SH
Source :
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2013 Mar 21; Vol. 49 (23), pp. 2287-9.
Publication Year :
2013

Abstract

The development of a new class of surfactants for membrane protein manipulation, "GNG amphiphiles", is reported. These amphiphiles display promising behavior for membrane proteins, as demonstrated recently by the high resolution structure of a sodium-pumping pyrophosphatase reported by Kellosalo et al. (Science, 2012, 337, 473).

Details

Language :
English
ISSN :
1364-548X
Volume :
49
Issue :
23
Database :
MEDLINE
Journal :
Chemical communications (Cambridge, England)
Publication Type :
Academic Journal
Accession number :
23165475
Full Text :
https://doi.org/10.1039/c2cc36844g