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HIV-1 RNA shedding in the female genital tract is associated with reduced quantity of Lactobacilli in clinically asymptomatic HIV-positive women.

Authors :
Mane A
Kulkarni S
Ghate M
Risbud A
Thakar M
Source :
Diagnostic microbiology and infectious disease [Diagn Microbiol Infect Dis] 2013 Jan; Vol. 75 (1), pp. 112-4. Date of Electronic Publication: 2012 Nov 08.
Publication Year :
2013

Abstract

We quantified vaginal lactobacilli and determined their relationship with genital HIV-1 shedding and found a significant negative association between reduced quantity of lactobacilli and cervical HIV-1 viral load (r(2) = - 0.8900, P < 0.01), which may have implications of increased chances of sexual transmission of HIV-1 and genital infections.<br /> (Copyright © 2013 Elsevier Inc. All rights reserved.)

Details

Language :
English
ISSN :
1879-0070
Volume :
75
Issue :
1
Database :
MEDLINE
Journal :
Diagnostic microbiology and infectious disease
Publication Type :
Academic Journal
Accession number :
23142167
Full Text :
https://doi.org/10.1016/j.diagmicrobio.2012.09.009