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[Successful use of C1 esterase inhibitor in capillary leak syndrome].
- Source :
-
Der Anaesthesist [Anaesthesist] 2012 Nov; Vol. 61 (11), pp. 954-7. - Publication Year :
- 2012
-
Abstract
- This article reports the successful use of C1 esterase inhibitor in the treatment of capillary leak syndrome. The coincidence of exposure to latex during surgery and medication with ramipril led to prolonged shock complicated by secondary hyperfibrinolysis, capillary leak syndrome and multiple organ failure. Initial treatment according to relevant guidelines failed to stabilize the condition. Treatment was only successful after administration of 1,500 IU of human C1 esterase inhibitor.
- Subjects :
- Anesthesia
Angiotensin-Converting Enzyme Inhibitors adverse effects
Angiotensin-Converting Enzyme Inhibitors therapeutic use
Aortic Aneurysm surgery
Disseminated Intravascular Coagulation complications
Disseminated Intravascular Coagulation therapy
Drug Hypersensitivity drug therapy
Humans
Intraoperative Complications therapy
Latex Hypersensitivity complications
Latex Hypersensitivity therapy
Male
Middle Aged
Multiple Organ Failure drug therapy
Ramipril adverse effects
Ramipril therapeutic use
Shock drug therapy
Capillary Leak Syndrome drug therapy
Complement C1 Inhibitor Protein therapeutic use
Subjects
Details
- Language :
- German
- ISSN :
- 1432-055X
- Volume :
- 61
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- Der Anaesthesist
- Publication Type :
- Academic Journal
- Accession number :
- 23135769
- Full Text :
- https://doi.org/10.1007/s00101-012-2092-3