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Massive fat and necrotic bone marrow embolization in a previously undiagnosed patient with sickle cell disease.
- Source :
-
The American journal of forensic medicine and pathology [Am J Forensic Med Pathol] 1990 Mar; Vol. 11 (1), pp. 83-8. - Publication Year :
- 1990
-
Abstract
- A case of sickle cell disease diagnosed postmortem is described. A 37-year-old black woman presented with anemia, respiratory distress, and abdominal and back pain. Death followed an intramuscular injection of iron, and anaphylaxis was clinically diagnosed. At autopsy, massive fat and necrotic bone marrow embolization of pulmonary and renal vessels was found. In the vertebral column, multifocal areas of ischemic necrosis were present, and proved to be the source of this embolization. Sickled red cells appeared in bone marrow sinusoids, and signs of disseminated intravascular coagulation were present.
- Subjects :
- Adult
Anaphylaxis diagnosis
Anemia, Sickle Cell complications
Anemia, Sickle Cell pathology
Diagnosis, Differential
Disseminated Intravascular Coagulation etiology
Disseminated Intravascular Coagulation pathology
Embolism etiology
Embolism, Fat etiology
Female
Humans
Infarction complications
Infarction pathology
Iron administration & dosage
Necrosis
Anemia, Sickle Cell diagnosis
Bone Marrow pathology
Embolism pathology
Embolism, Fat pathology
Subjects
Details
- Language :
- English
- ISSN :
- 0195-7910
- Volume :
- 11
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- The American journal of forensic medicine and pathology
- Publication Type :
- Academic Journal
- Accession number :
- 2305755
- Full Text :
- https://doi.org/10.1097/00000433-199003000-00013