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Ineffectiveness and comparative pathogenicity of attenuated rabies virus vaccines for the striped skunk (Mephitis mephitis).
- Source :
-
Journal of wildlife diseases [J Wildl Dis] 1990 Jan; Vol. 26 (1), pp. 99-102. - Publication Year :
- 1990
-
Abstract
- Three attenuated rabies virus vaccines (SAD-B19, ERA/BHK-21, AZA 2) were compared for efficacy and safety in the striped skunk (Mephitis mephitis) by the oral and intranasal routes. The SAD-B19 and ERA/BHK-21 vaccines were given orally; all three vaccines were given intranasally. Oral administration of SAD-B19 and ERA/BHK-21 vaccines induced neither seroconversion nor significant protection against rabies challenge. One skunk which consumed a SAD-B19 vaccine-laden bait succumbed to vaccine-induced rabies. Intranasal instillation of the three vaccines resulted in the deaths of two of six (AZA 2), three of six (ERA/BHK-21) and six of six (SAD-B19) skunks.
- Subjects :
- Administration, Intranasal
Administration, Oral
Animals
Antibodies, Viral biosynthesis
Female
Male
Rabies prevention & control
Rabies Vaccines administration & dosage
Rabies Vaccines immunology
Rabies virus immunology
Vaccines, Attenuated administration & dosage
Vaccines, Attenuated adverse effects
Vaccines, Attenuated immunology
Carnivora
Mephitidae
Rabies veterinary
Rabies Vaccines adverse effects
Subjects
Details
- Language :
- English
- ISSN :
- 0090-3558
- Volume :
- 26
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Journal of wildlife diseases
- Publication Type :
- Academic Journal
- Accession number :
- 2304207
- Full Text :
- https://doi.org/10.7589/0090-3558-26.1.99