Back to Search
Start Over
Genotoxicity of digital panoramic radiography on oral epithelial tissues.
- Source :
-
Quintessence international (Berlin, Germany : 1985) [Quintessence Int] 2012 Sep; Vol. 43 (8), pp. 719-25. - Publication Year :
- 2012
-
Abstract
- Objective: To evaluate the genotoxic effects of x-rays on gingival and buccal epithelial cells during panoramic dental radiography using the micronucleus test.<br />Method and Materials: Eighty otherwise healthy subjects who required a diagnostic panoramic radiograph and met the selection criteria were included in the study. Epithelial cells were obtained from the maxillary anterior gingiva and buccal mucosa by gentle scraping with a wooden spatula immediately before exposure and again 10 days after exposure. Cytologic preparations were made according to the Papanicolaou staining method and analyzed under a light microscope for micronucleus count.<br />Results: The mean ± SD micronucleus count of gingival epithelial cells was 1.08 ± 0.76 before radiographic exposure and 1.6 ± 0.93 after exposure. This increase was statistically significant (P < .05). Similarly, there was an increase in the postexposure micronucleus count in the buccal mucosa, but this increase was not significant (P > .05). A significant correlation was observed between the age of subjects and micronucleus count, although no such correlation was found between sex and micronucleus count.<br />Conclusion: Although radiation-related effects from panoramic radiography were reduced compared with full-mouth intraoral periapical radiographs or radiotherapy, the results of this study show that genotoxic effects do take place. Thus, radiographs should be taken with adequate protection measures and only when the potential benefit outweighs the potential risk.
- Subjects :
- Adolescent
Adult
Age Factors
Epithelial Cells radiation effects
Female
Gingiva cytology
Humans
Male
Micronucleus Tests
Middle Aged
Mouth Mucosa cytology
Statistics, Nonparametric
Young Adult
DNA Damage
Gingiva radiation effects
Mouth Mucosa radiation effects
Radiography, Dental, Digital adverse effects
Radiography, Panoramic adverse effects
Subjects
Details
- Language :
- English
- ISSN :
- 1936-7163
- Volume :
- 43
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Quintessence international (Berlin, Germany : 1985)
- Publication Type :
- Academic Journal
- Accession number :
- 23034425