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[Antiherpetic activity of netropsin derivatives as tested in experiments in laboratory animals].
- Source :
-
Voprosy virusologii [Vopr Virusol] 2012 Jul-Aug; Vol. 57 (4), pp. 24-6. - Publication Year :
- 2012
-
Abstract
- Two dimeric netropsin derivatives (Lys-bis-Nt 15Lys-bis-Nt) were comprehensively tested for antiviral and toxic activity in cell cultures and laboratory animals. The two compounds were found to provide effective and selective inhibition of reproduction of herpes simplex I both in cell culture Vero E6 and in brain of infected white mice, thereby increasing the survival rate and mean life expectation of treated animals as compared to control.
Details
- Language :
- Russian
- ISSN :
- 0507-4088
- Volume :
- 57
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Voprosy virusologii
- Publication Type :
- Academic Journal
- Accession number :
- 23012980