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Five-year follow-up of 16 melanoma patients with a Starz I-involved sentinel node in whom completion lymph node dissection was omitted.

Authors :
Veenstra HJ
Brouwer OR
van der Ploeg IM
Kroon BB
Nieweg OE
Source :
Melanoma research [Melanoma Res] 2012 Dec; Vol. 22 (6), pp. 436-9.
Publication Year :
2012

Abstract

The aim of the study was to determine the incidence of lymph node recurrence in 16 melanoma patients with a minimal metastasis (Starz level I) in a sentinel node in whom a completion lymph node dissection was omitted. A secondary aim was to examine whether other melanoma-related recurrences developed. Sixteen melanoma patients with an SI-involved sentinel node, who did not undergo completion lymph node dissection, were followed for a median of 66 months. Lymph node recurrences did not occur. One of the 16 patients developed a local recurrence and another developed satellite metastases. None of the 16 patients with an SI-positive sentinel node developed a nodal recurrence, which suggests that the risk of refraining from node dissection in such patients is small. This option could be considered and discussed with the patient in terms of the risk of nonsentinel node involvement and the unsolved problem of unknown overall survival advantage.

Details

Language :
English
ISSN :
1473-5636
Volume :
22
Issue :
6
Database :
MEDLINE
Journal :
Melanoma research
Publication Type :
Academic Journal
Accession number :
22975764
Full Text :
https://doi.org/10.1097/CMR.0b013e328358da2d