[Imaging non motor signs in Parkinson's disease].

Authors :: Thobois S
Ballanger B
Poisson A
Broussolle E
Source :: Revue neurologique [Rev Neurol (Paris)] 2012 Aug-Sep; Vol. 168 (8-9), pp. 576-84. Date of Electronic Publication: 2012 Aug 24.
Publication Year :: 2012
Abstract: Parkinson's disease is mainly considered as a motor disorder defined by a motor triad. However, various non-motor manifestations may be encountered in Parkinson's disease, including hyposmia, pain, fatigue, sleep disorders, cognitive and behavioral disorders. The pathophysiology of these signs is complex, not univocal and remains poorly understood. Functional imaging techniques either by positron emission tomography, single photon emission tomography or functional magnetic resonance imaging provide an invaluable opportunity to better understand the pathophysiology of these signs. In this paper, we present a review of the recent advances provided by functional imaging in this area.<br /> (Copyright © 2012 Elsevier Masson SAS. All rights reserved.)