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[Implantation of embryonic neocortex and spinal cord into injured peripheral nerve of adult rats].
- Source :
-
Biulleten' eksperimental'noi biologii i meditsiny [Biull Eksp Biol Med] 1990 Aug; Vol. 110 (8), pp. 198-201. - Publication Year :
- 1990
-
Abstract
- Spinal cord and cerebral cortex of 14-day-old embryos of Wistar rats were implanted into the sciatic nerve of mature rats in order to study dynamics of the development of neuronal and neuroglial elements in ectopic sites. By means of light and electron microscopy it has been stated that the implanted nerve cells of the cortex and spinal cord survive during 5 month and differentiate from neuroepithelial cells and neuroblasts up to young and mature neurons. It was found that thirty days after operation the spinal cord implants contained myelinated nerve fibers and numerous synapses. The data obtained suggest that the implants of fetal spinal cord are more favorable for regeneration of the injured nervous stems than the cerebral cortex.
- Subjects :
- Animals
Cerebral Cortex ultrastructure
Embryo, Mammalian
Gestational Age
Male
Nerve Fibers, Myelinated ultrastructure
Nerve Regeneration
Peripheral Nerve Injuries
Rats
Rats, Inbred Strains
Sciatic Nerve injuries
Spinal Cord ultrastructure
Synapses ultrastructure
Cerebral Cortex transplantation
Peripheral Nerves
Spinal Cord transplantation
Subjects
Details
- Language :
- Russian
- ISSN :
- 0365-9615
- Volume :
- 110
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Biulleten' eksperimental'noi biologii i meditsiny
- Publication Type :
- Academic Journal
- Accession number :
- 2291972