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[Implantation of embryonic neocortex and spinal cord into injured peripheral nerve of adult rats].

Authors :
Chumasov EI
Petrova ES
Source :
Biulleten' eksperimental'noi biologii i meditsiny [Biull Eksp Biol Med] 1990 Aug; Vol. 110 (8), pp. 198-201.
Publication Year :
1990

Abstract

Spinal cord and cerebral cortex of 14-day-old embryos of Wistar rats were implanted into the sciatic nerve of mature rats in order to study dynamics of the development of neuronal and neuroglial elements in ectopic sites. By means of light and electron microscopy it has been stated that the implanted nerve cells of the cortex and spinal cord survive during 5 month and differentiate from neuroepithelial cells and neuroblasts up to young and mature neurons. It was found that thirty days after operation the spinal cord implants contained myelinated nerve fibers and numerous synapses. The data obtained suggest that the implants of fetal spinal cord are more favorable for regeneration of the injured nervous stems than the cerebral cortex.

Details

Language :
Russian
ISSN :
0365-9615
Volume :
110
Issue :
8
Database :
MEDLINE
Journal :
Biulleten' eksperimental'noi biologii i meditsiny
Publication Type :
Academic Journal
Accession number :
2291972