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The hairy-print for levamisole-induced vasculitis.
- Source :
-
BMJ case reports [BMJ Case Rep] 2012 Aug 08; Vol. 2012. Date of Electronic Publication: 2012 Aug 08. - Publication Year :
- 2012
-
Abstract
- Levamisole-induced vasculitis is a well-characterised antineutrophil cytoplasm antibodies (ANCA)-positive vasculitis in cocaine abuser patients. However, due to the short half-life of levamisole in serum and urine, the causal role of levamisole is not established. Here we report the detection of both levamisole and cocaine in hair samples of a patient who presented with an ANCA-positive vasculitis. The higher concentration of levamisole in proximal sample of the hair confirms that the patient abused of cocaine added with levamisole in the days preceding the development of skin lesions. Although a direct causative role has not been established, our report strongly suggests that levamisole may have triggered vasculitis in this case.
- Subjects :
- Adjuvants, Immunologic analysis
Adult
Arthralgia chemically induced
Cocaine adverse effects
Female
Fever chemically induced
Humans
Medication Adherence
Methotrexate therapeutic use
Prednisone therapeutic use
Rhinitis chemically induced
Treatment Outcome
Vasculitis chemically induced
Vasculitis immunology
Cocaine analysis
Cocaine-Related Disorders complications
Hair chemistry
Levamisole analysis
Skin chemistry
Vasculitis pathology
Subjects
Details
- Language :
- English
- ISSN :
- 1757-790X
- Volume :
- 2012
- Database :
- MEDLINE
- Journal :
- BMJ case reports
- Publication Type :
- Academic Journal
- Accession number :
- 22879002
- Full Text :
- https://doi.org/10.1136/bcr-2012-006602