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On the use of ultracentrifugal devices for sedimented solute NMR.
- Source :
-
Journal of biomolecular NMR [J Biomol NMR] 2012 Oct; Vol. 54 (2), pp. 123-7. Date of Electronic Publication: 2012 Aug 08. - Publication Year :
- 2012
-
Abstract
- We have recently proposed sedimented solute NMR (SedNMR) as a solid-state method to access biomolecules without the need of crystallization or other sample manipulation. The drawback of SedNMR is that samples are intrinsically diluted and this is detrimental for the signal intensity. Ultracentrifugal devices can be used to increase the amount of sample inside the rotor, overcoming the intrinsic sensitivity limitation of the method. We designed two different devices and we here report the directions for using such devices and the relevant equations for determining the parameters for sedimentation.
Details
- Language :
- English
- ISSN :
- 1573-5001
- Volume :
- 54
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Journal of biomolecular NMR
- Publication Type :
- Academic Journal
- Accession number :
- 22872367
- Full Text :
- https://doi.org/10.1007/s10858-012-9657-y