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Annona montana fruit and leaves improve the glycemic and lipid profiles of Wistar rats.
- Source :
-
Journal of medicinal food [J Med Food] 2012 Oct; Vol. 15 (10), pp. 917-22. Date of Electronic Publication: 2012 Aug 02. - Publication Year :
- 2012
-
Abstract
- Species of the family Annonaceae has been used traditionally as a medicinal plant in tropical regions of South and North America and in Africa. Annona montana is known popularly as false graviola and originates from tropical America and can be cultivated throughout Brazil. There are no studies in the literature that associate A. montana with the metabolic profile of animals. Therefore, the purpose of this work was to assess the effects of the consumption of pulp and leaves of this plant on the metabolic profile of Wistar rats. The animals, which were treated for 40 days, were divided into two control groups--treated with water via gavage and ad libitum, respectively, and two treated groups--one treated with leaf juice and the other with pulp juice of the fruit. Glycemia, lipids, and body weight were found to decrease and high density lipoprotein-cholesterol (HDL-c) levels to increase in the animals treated with leaf juice. The group treated with pulp juice showed a reduction in lipids and augmented HDL-c. The use of A. montana may have beneficial effects in the prevention of diabetes mellitus and dyslipidemia and may thus contribute to the prevention of cardiovascular diseases.
- Subjects :
- Africa
Animals
Beverages
Blood Glucose metabolism
Body Weight drug effects
Brazil
Diabetes Mellitus, Experimental drug therapy
Diabetes Mellitus, Experimental prevention & control
Dyslipidemias drug therapy
Dyslipidemias prevention & control
Male
North America
Plants, Medicinal chemistry
Rats
Rats, Wistar
Annona chemistry
Blood Glucose drug effects
Cholesterol, HDL blood
Fruit chemistry
Plant Extracts pharmacology
Plant Leaves chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 1557-7600
- Volume :
- 15
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Journal of medicinal food
- Publication Type :
- Academic Journal
- Accession number :
- 22856324
- Full Text :
- https://doi.org/10.1089/jmf.2012.0088