Precocious puberty in Turner syndrome variant.

Authors :: Baek JU
Park HK
Shim EJ
Hwang IT
Source :: Journal of pediatric and adolescent gynecology [J Pediatr Adolesc Gynecol] 2012 Oct; Vol. 25 (5), pp. e113-4. Date of Electronic Publication: 2012 Jul 27.
Publication Year :: 2012
Abstract: Background: Turner syndrome is due to the absence of all or significant parts of one of the sex chromosomes in females. Turner syndrome is a common cause of ovarian failure, and hypergonadotropic hypogonadism occurs in virtually all affected individuals. One case of a variant Turner syndrome with precocious puberty is presented.<br />Case: An eight-year-old girl was referred with complaints of short stature and breast budding. A physical examination revealed a Tanner stage III for breast development and her bone age was 11 years. Chromosome analysis showed a karyotype of 46,X,del(x)(p11.2).<br />Summary and Conclusion: To preserve growth potential, careful examinations are recommended for pediatric patients with an unusual growth pattern.<br /> (Copyright © 2012 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved.)