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ST peak during primary percutaneous coronary intervention predicts final infarct size, left ventricular function, and clinical outcome.
- Source :
-
Journal of electrocardiology [J Electrocardiol] 2012 Nov-Dec; Vol. 45 (6), pp. 708-16. Date of Electronic Publication: 2012 Jul 24. - Publication Year :
- 2012
-
Abstract
- Background and Purpose: One third of patients treated with primary percutaneous coronary intervention (PCI) for ST-elevation myocardial infarction develop a secondary increase in electrocardiographic ST segment (ST peak) during reperfusion. The purpose was to determine the clinical importance of ST peak during primary PCI.<br />Methods: A total of 363 patients with ST-elevation myocardial infarction were stratified to no ST peak or ST peak. Final infarct size and ejection fraction (EF) were assessed by cardiovascular magnetic resonance.<br />Results: Patients with ST peak had a larger infarct size (14% vs 10%; P = .003) and lower EF (53% vs 57%; P = .022). Rates of cardiac mortality (8% vs 3%; P = .047) and cardiac events (cardiac mortality and admission for heart failure; 19% vs 10%; P = .018) were higher among patients with ST peak, but not all-cause mortality (8% vs 5%; P = .46). In a multivariable Cox regression analysis, ST peak remained significantly associated with cardiac events (adjusted hazard ratio, 2.03 [1.08-3.82]).<br />Conclusion: ST peak during primary PCI is related to larger final infarct size, a reduced EF, and adverse cardiac clinical outcome.<br /> (Copyright © 2012 Elsevier Inc. All rights reserved.)
- Subjects :
- Comorbidity
Denmark epidemiology
Female
Humans
Male
Myocardial Infarction diagnosis
Prevalence
Prognosis
Reproducibility of Results
Risk Assessment
Sensitivity and Specificity
Survival Analysis
Survival Rate
Treatment Outcome
Ventricular Dysfunction, Left diagnosis
Electrocardiography statistics & numerical data
Myocardial Infarction mortality
Myocardial Infarction surgery
Percutaneous Coronary Intervention mortality
Ventricular Dysfunction, Left mortality
Ventricular Dysfunction, Left prevention & control
Subjects
Details
- Language :
- English
- ISSN :
- 1532-8430
- Volume :
- 45
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Journal of electrocardiology
- Publication Type :
- Academic Journal
- Accession number :
- 22832151
- Full Text :
- https://doi.org/10.1016/j.jelectrocard.2012.06.028