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Molecular epidemiology of human metapneumovirus from 2009 to 2011 in Okinawa, Japan.
- Source :
-
Japanese journal of infectious diseases [Jpn J Infect Dis] 2012 Jul; Vol. 65 (4), pp. 337-40. - Publication Year :
- 2012
-
Abstract
- To clarify the molecular epidemiology of human metapneumovirus (HMPV) in Okinawa Prefecture, located in a subtropical region of Japan, we performed genetic analysis of the F gene in HMPV from patients with acute respiratory infection from January 2009 to December 2011. HMPV was detected in 18 of 485 throat swabs (3.7%). Phylogenetic analysis showed that 17 strains belonged to subgroup A2 and 1 strain belonged to subgroup B1. We did not observe seasonal prevalence of HMPV during the investigation period. A high level of sequence identity was observed in the strains belonging to subgroup A2 (>95%), and no amino acid substitution was found compared with other strains detected in Japan and other countries. The pairwise distance values among the present strains belonging to subgroup A2 were short. Our results suggest that the predominant HMPV strains belonging to A2 are highly homologous and seasonal epidemics were not seen in Okinawa during the investigation period.
- Subjects :
- Child
Child, Preschool
Genes, Viral
Humans
Infant
Infant, Newborn
Japan epidemiology
Metapneumovirus classification
Paramyxoviridae Infections virology
Phylogeny
Respiratory Tract Infections virology
Seasons
Metapneumovirus genetics
Paramyxoviridae Infections epidemiology
Respiratory Tract Infections epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 1884-2836
- Volume :
- 65
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Japanese journal of infectious diseases
- Publication Type :
- Academic Journal
- Accession number :
- 22814160
- Full Text :
- https://doi.org/10.7883/yoken.65.337