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A new rat model of reversible global cerebral ischemia.
- Source :
-
Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2012 Mar; Vol. 152 (5), pp. 656-8. - Publication Year :
- 2012
-
Abstract
- A new rat model of global cerebral ischemia-reperfusion was proposed via reversible occlusion of the major vessels originating from the aortic arch and supplying the brain. This technique can be used for the search and study of exogenous (pharmacological) and endogenous methods of brain protection from ischemia-reperfusion injury.
- Subjects :
- Animals
Aorta physiopathology
Brain physiopathology
Brain Ischemia mortality
Brain Ischemia physiopathology
Carotid Arteries physiopathology
Disease Models, Animal
Histocytochemistry
Ligation
Male
Rats
Rats, Wistar
Reperfusion Injury mortality
Reperfusion Injury physiopathology
Survival Rate
Aorta pathology
Brain pathology
Brain Ischemia pathology
Carotid Arteries pathology
Reperfusion Injury pathology
Subjects
Details
- Language :
- English; Russian
- ISSN :
- 1573-8221
- Volume :
- 152
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Bulletin of experimental biology and medicine
- Publication Type :
- Academic Journal
- Accession number :
- 22803158
- Full Text :
- https://doi.org/10.1007/s10517-012-1600-4