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[Cardiac sinus node dysfunction due to a new mutation of the SCN5A gene].

Authors :
Selly JB
Boumahni B
Edmar A
Jamal Bey K
Randrianaivo H
Clerici G
Millat G
Caillet D
Source :
Archives de pediatrie : organe officiel de la Societe francaise de pediatrie [Arch Pediatr] 2012 Aug; Vol. 19 (8), pp. 837-41. Date of Electronic Publication: 2012 Jul 12.
Publication Year :
2012

Abstract

A 10-year-old child was hospitalized for bradycardia during a viral infection with chikungunya. His history showed unexplored episodes of bradycardia. Cardiologic explorations revealed cardiac sinus node dysfunction (SD). Mutational screening of the SCN5A gene showed that this case was a compound heterozygote for p.Ala735Val and p.Asp1792Asn missense mutants. Five years later, the child underwent a pacemaker insertion after an electrophysiological study performed during an atrial flutter access.<br /> (Copyright © 2012 Elsevier Masson SAS. All rights reserved.)

Details

Language :
French
ISSN :
1769-664X
Volume :
19
Issue :
8
Database :
MEDLINE
Journal :
Archives de pediatrie : organe officiel de la Societe francaise de pediatrie
Publication Type :
Academic Journal
Accession number :
22795782
Full Text :
https://doi.org/10.1016/j.arcped.2012.04.017