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[Bactericidal activity of ofloxacin against Mycobacterium kansasii].
- Source :
-
Kekkaku : [Tuberculosis] [Kekkaku] 1990 Nov; Vol. 65 (11), pp. 719-21. - Publication Year :
- 1990
-
Abstract
- Bactericidal activity of ofloxacin against Mycobacterium kansasii was observed in in-vitro experiment. Tested bacteria were suspended to a concentration of one mg wet weight per ml in 10 ml of Dubos liquid medium containing no drug or containing 1 or 3 micrograms/ml ofloxacin and incubated at 37 degrees C. The number of colony-forming units contained in a 0.02 ml-sample of the Dubos liquid medium was counted after incubation for 0, 1, 3 and 7 days. The number of colonies was counted in Ogawa egg medium, to which was inoculated a 0.02 ml-sample of dilutions of the medium by a spiral loop that can deliver a 0.02 ml-sample by one inoculation. The bactericidal activity of ofloxacin against M. kansasii appeared after incubation of 3 days or later. This characteristic was different from the bactericidal activity against Mycobacterium tuberculosis, which appeared after incubation of 24 hours.
Details
- Language :
- Japanese
- ISSN :
- 0022-9776
- Volume :
- 65
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- Kekkaku : [Tuberculosis]
- Publication Type :
- Academic Journal
- Accession number :
- 2277465