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Fabrication of glutathione photoelectrochemical biosensor using graphene-CdS nanocomposites.
- Source :
-
The Analyst [Analyst] 2012 Aug 21; Vol. 137 (16), pp. 3697-703. Date of Electronic Publication: 2012 Jul 09. - Publication Year :
- 2012
-
Abstract
- A novel glutathione (GSH) photoelectrochemical biosensor was fabricated using the newly synthesized graphene-CdS (GR-CdS) nanocomposites. The GR-CdS nanocomposites were prepared by a fast, one-step, aqueous reaction. The as-prepared GR-CdS structure inherited the excellent electron transport of GR and facilitated the spatial separation of photo-generated charge carrier, therefore resulting in the enhanced photocurrent, and making it a promising candidate for developing photoelectrochemical biosensors. The proposed GSH sensor displays satisfactory analytical performance with an acceptable linear range from 0.01 to 1.5 mmol L(-1) with a detection limit of 0.003 mmol L(-1) at a signal-to-noise ratio of 3, and also shows an excellent specificity against anticancer drugs and can be successfully applied for GSH detection in real samples. The as-synthesized GR-CdS nanocomposites exhibited obviously enhanced photovoltaic properties, which could be extended to the detection of other enzymes and biomolecules, thus providing a promising platform for the development of photoelectrochemical biosensors.
- Subjects :
- Models, Molecular
Molecular Conformation
Ophthalmic Solutions analysis
Ophthalmic Solutions chemistry
Oxidation-Reduction
Biosensing Techniques methods
Cadmium Compounds chemistry
Electrochemistry methods
Glutathione chemistry
Graphite chemistry
Nanostructures chemistry
Photochemical Processes
Sulfides chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 1364-5528
- Volume :
- 137
- Issue :
- 16
- Database :
- MEDLINE
- Journal :
- The Analyst
- Publication Type :
- Academic Journal
- Accession number :
- 22774001
- Full Text :
- https://doi.org/10.1039/c2an35658a