Autoantibodies to the thyrotrophin receptor mimic thyrotrophin in stimulating both thyroglobulin and thyroid peroxidase mRNA transcription in human thyroid cells.

Authors :: Collison KS
Banga JP
Barnett PS
Huang GC
McGregor AM
Source :: Biochemical Society transactions [Biochem Soc Trans] 1990 Aug; Vol. 18 (4), pp. 559-60.
Publication Year :: 1990

Subjects :: Cells, Cultured
Graves Disease immunology
Graves Disease metabolism
Humans
Iodide Peroxidase genetics
RNA, Messenger genetics
RNA, Messenger metabolism
Thyroglobulin genetics
Thyroid Gland drug effects
Thyrotropin pharmacology
Transcription, Genetic drug effects
Autoantibodies metabolism
Receptors, Thyrotropin immunology
Thyroid Gland metabolism

Full Text Access

Tools