Intravenous fluorescein as a cause of immunoglobulin E-mediated anaphylactic shock.

Authors :: Breidablik A
De Pater GH
Walther C
Nopp A
Guttormsen AB
Source :: Acta anaesthesiologica Scandinavica [Acta Anaesthesiol Scand] 2012 Sep; Vol. 56 (8), pp. 1066-8. Date of Electronic Publication: 2012 Jul 04.
Publication Year :: 2012
Abstract: We report a patient with severe anaphylactic shock immediately after injection of i.v. fluorescein. The patient recovered without sequela. Immunoglobulin E (IgE) mechanism was highly suggestive with significant increase in serum tryptase, positive basophil allergen threshold sensitivity (CD-sens) and histamine release tests towards fluorescein. This is, to our knowledge, the first report where CD-sens has been used to aid in diagnosing an IgE-mediated anaphylactic shock caused by fluorescein.<br /> (© 2012 The Authors. Acta Anaesthesiologica Scandinavica © 2012 The Acta Anaesthesiologica Scandinavica Foundation.)

Subjects :: Aged
Anaphylaxis drug therapy
Anaphylaxis etiology
Antigens, CD immunology
Basophils immunology
Chest Pain complications
Epinephrine therapeutic use
Histamine Release physiology
Humans
Intubation, Intratracheal
Male
Mucus physiology
Skin Tests
Tryptases
Vasoconstrictor Agents therapeutic use
Anaphylaxis immunology
Contrast Media adverse effects
Fluorescein adverse effects
Immunoglobulin E immunology

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