Occurrence and molecular characterization of Klebsiella pneumoniae ST37 clinical isolates producing plasmid-mediated AmpC recovered over a 3-year period.

Authors :: Illiaquer M
Caroff N
Bémer P
Aubin GG
Juvin ME
Lepelletier D
Reynaud A
Corvec S
Source :: Diagnostic microbiology and infectious disease [Diagn Microbiol Infect Dis] 2012 Sep; Vol. 74 (1), pp. 95-7. Date of Electronic Publication: 2012 Jun 28.
Publication Year :: 2012
Abstract: We investigated the clinical and microbiological epidemiology of AmpC plasmidic cephalosporinases (pAmpC) in Klebsiella pneumoniae strains resistant to ceftazidime, during a 3-year period (2007-2009). Among 1505 K. pneumoniae, 7 were pAmpC producers. Molecular characterization revealed the spread of a ST37 strain producing DHA-1 within intensive care units and the diffusion of the same plasmid among unrelated strains.<br /> (Copyright © 2012 Elsevier Inc. All rights reserved.)

Subjects :: Adult
Aged
Anti-Bacterial Agents pharmacology
Ceftazidime pharmacology
Female
Humans
Klebsiella pneumoniae drug effects
Klebsiella pneumoniae isolation & purification
Male
Microbial Sensitivity Tests
Middle Aged
Molecular Epidemiology
beta-Lactam Resistance
Bacterial Proteins genetics
Klebsiella Infections epidemiology
Klebsiella pneumoniae enzymology
Klebsiella pneumoniae genetics
Plasmids
beta-Lactamases genetics

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