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Using an electrical potential to reversibly switch surfaces between two states for dynamically controlling cell adhesion.

Authors :
Ng CC
Magenau A
Ngalim SH
Ciampi S
Chockalingham M
Harper JB
Gaus K
Gooding JJ
Source :
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2012 Jul 27; Vol. 51 (31), pp. 7706-10. Date of Electronic Publication: 2012 Jun 22.
Publication Year :
2012

Abstract

Smart surfaces presenting both antifouling molecules with a charged functional group at their distal end, and molecules that are terminated by RGD peptides for cell adhesion, were fabricated and characterized (see picture). By applying potentials of +300 or -300 mV, the surfaces could be dynamically switched to make the peptide accessible or inaccessible to cells.<br /> (Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.)

Details

Language :
English
ISSN :
1521-3773
Volume :
51
Issue :
31
Database :
MEDLINE
Journal :
Angewandte Chemie (International ed. in English)
Publication Type :
Academic Journal
Accession number :
22730419
Full Text :
https://doi.org/10.1002/anie.201202118