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Screening, prevention, and treatment for hyperinfection syndrome and disseminated infections caused by Strongyloides stercoralis.
- Source :
-
Current opinion in infectious diseases [Curr Opin Infect Dis] 2012 Aug; Vol. 25 (4), pp. 458-63. - Publication Year :
- 2012
-
Abstract
- Purpose of Review: This review discusses the latest approaches to the diagnosis and treatment of patients with strongyloidiasis, with an emphasis on infection in the immunocompromised host and the risk for disseminated strongyloidiasis.<br />Recent Findings: The differences in acute, chronic, accelerated autoinfection, and disseminated disease in Strongyloides stercoralis infection are explored with particular emphasis on early diagnosis, treatment, and prevention. The goals of treatment are investigated for the different infection states. Predisposing risks for dissemination are delineated, and the roles played for newer diagnostics in the identification of at-risk individuals are detailed.<br />Summary: The use of newer diagnostic tests and broader screening of immunocompromised patients from Strongyloides-endemic areas is of paramount importance, particularly if prevention of life-threatening dissemination is the goal.
- Subjects :
- Acute Disease
Animals
Antinematodal Agents therapeutic use
Chronic Disease
Early Diagnosis
Humans
Immunocompromised Host
Immunosuppressive Agents therapeutic use
Risk Factors
Strongyloides stercoralis physiology
Strongyloidiasis diagnosis
Strongyloidiasis drug therapy
Strongyloidiasis prevention & control
Subjects
Details
- Language :
- English
- ISSN :
- 1473-6527
- Volume :
- 25
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Current opinion in infectious diseases
- Publication Type :
- Academic Journal
- Accession number :
- 22691685
- Full Text :
- https://doi.org/10.1097/QCO.0b013e3283551dbd