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[Protective action of Salvia miltiorrhiza aqueous extract on chemically induced acute myocardial ischemia in rats].

[Protective action of Salvia miltiorrhiza aqueous extract on chemically induced acute myocardial ischemia in rats].

Authors :
Cheng YY
Fong SM
Chang HM
Source :
Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine [Zhong Xi Yi Jie He Za Zhi] 1990 Oct; Vol. 10 (10), pp. 609-11, 582.
Publication Year :
1990

Abstract

Aqueous extract of Salvia miltiorrhiza (SM-H) can protect the acute myocardial ischemia and arrhythmia of Sprague-Dawley rats induced by isoproterenol (ISO) or BaCl2 with the following results: (1) intraperitoneal injection (i.p.) of SM-H for 3 to 5 days or intravenously (i.v.) just once significantly reduced the death rate of the animals, (2) i.v. SM-H pretreatment significantly increased the lethal dose of BaCl2 infusion, (3) i.p. SM-H significantly decreased premature ventricular contraction, ventricular fibrillation, bradycardia and mortality rate induced by bolus i.v. of BaCl2, and (4) i.p. SM-H also significantly reduced ECG J-point displacement of rats induced by ISO.

Details

Language :
Chinese
ISSN :
0254-9034
Volume :
10
Issue :
10
Database :
MEDLINE
Journal :
Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine
Publication Type :
Academic Journal
Accession number :
2268921