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[Protective action of Salvia miltiorrhiza aqueous extract on chemically induced acute myocardial ischemia in rats].
[Protective action of Salvia miltiorrhiza aqueous extract on chemically induced acute myocardial ischemia in rats].
- Source :
-
Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine [Zhong Xi Yi Jie He Za Zhi] 1990 Oct; Vol. 10 (10), pp. 609-11, 582. - Publication Year :
- 1990
-
Abstract
- Aqueous extract of Salvia miltiorrhiza (SM-H) can protect the acute myocardial ischemia and arrhythmia of Sprague-Dawley rats induced by isoproterenol (ISO) or BaCl2 with the following results: (1) intraperitoneal injection (i.p.) of SM-H for 3 to 5 days or intravenously (i.v.) just once significantly reduced the death rate of the animals, (2) i.v. SM-H pretreatment significantly increased the lethal dose of BaCl2 infusion, (3) i.p. SM-H significantly decreased premature ventricular contraction, ventricular fibrillation, bradycardia and mortality rate induced by bolus i.v. of BaCl2, and (4) i.p. SM-H also significantly reduced ECG J-point displacement of rats induced by ISO.
- Subjects :
- Animals
Arrhythmias, Cardiac chemically induced
Arrhythmias, Cardiac drug therapy
Barium
Coronary Disease chemically induced
Drug Combinations
Isoproterenol
Male
Rats
Rats, Inbred Strains
Salvia miltiorrhiza
Barium Compounds
Chlorides
Coronary Disease drug therapy
Drugs, Chinese Herbal therapeutic use
Phenanthrolines therapeutic use
Plant Extracts
Subjects
Details
- Language :
- Chinese
- ISSN :
- 0254-9034
- Volume :
- 10
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine
- Publication Type :
- Academic Journal
- Accession number :
- 2268921