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Renal hypertension in rats with hereditary polycystic kidney disease.
- Source :
-
Zeitschrift fur Versuchstierkunde [Z Versuchstierkd] 1990; Vol. 33 (5), pp. 201-4. - Publication Year :
- 1990
-
Abstract
- Hereditary polycystic kidney disease (PKD) was observed in a Han:SPRD rat mutant. Cysts were of tubular origin and occurrence was more pronounced in males than in females. In male rats polycystic kidney disease was associated with a marked elevation of systolic blood pressure. Therefore this rat mutant can be considered as a laboratory animal model for renal hypertension associated with adult polycystic kidney disease in man.
Details
- Language :
- English
- ISSN :
- 0044-3697
- Volume :
- 33
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Zeitschrift fur Versuchstierkunde
- Publication Type :
- Academic Journal
- Accession number :
- 2267865