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[Bioinformatic research of the family of PEX11, peroxisome proliferous factor in fungus].

Authors :
Zhang X
Jiang H
Wang YL
Zhang Z
Mao XQ
Chai RY
Qiu HP
Du XF
Wang JY
Sun GC
Source :
Yi chuan = Hereditas [Yi Chuan] 2012 May; Vol. 34 (5), pp. 635-46.
Publication Year :
2012

Abstract

The family members of PEX11 are key factors involved in regulation of peroxisome proliferation. Sixty-six PEX11p candidates of PEX11 gene family from 26 representative fungal species were obtained and analyzed by bioinformatic strategies. In most filamentous fungi, 2 or 3 potential PEX11ps were found, in contrast with 1 or 2 in yeast species. Compared with other fungal species, the Ascomycetes tend to have more PEX11ps, and even 5 in several individuals. The data of phylogenetic analysis and protein structure indicated that all of the PEX11ps were divided into 3 groups: I, II, and III. The members of group I and group III existed in most species, while those in group II were found only in Pezizomycotina. By MEME analysis, 5-6 conserved motifs were found in each PEX11ps. Among them,motif 8 in C-terminal had the most conservation, indicating that this motif probably plays a key role in maintaining the proper function of PEX11p.

Details

Language :
Chinese
ISSN :
0253-9772
Volume :
34
Issue :
5
Database :
MEDLINE
Journal :
Yi chuan = Hereditas
Publication Type :
Academic Journal
Accession number :
22659436
Full Text :
https://doi.org/10.3724/sp.j.1005.2012.00635