Lack of correlation between blood lead and serum prolactin levels among lead exposed workers.

Authors :: Catalani S
De Palma G
Tomasi C
Alinovi R
Mutti A
Apostoli P
Source :: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals [Biomarkers] 2012 Sep; Vol. 17 (6), pp. 513-9. Date of Electronic Publication: 2012 May 30.
Publication Year :: 2012
Abstract: A cross sectional case (241 males occupationally exposed to lead)-control (102 males unexposed to lead) study was performed with the aim of evaluating the relationship between serum prolactin (S-PRL) and lead blood (PbB) levels. A meta-analysis of S-PRL levels in similar studies was also carried out. No difference of S-PRL between groups or any relationship between PbB and S-PRL levels was found. The meta-analysis showed a slight increase of S-PRL levels among exposed people, the weighted means falling within the reference values of the biomarker. The results do not support a routine use of S-PRL as a biomarker of effect in lead exposed workers.

Subjects :: Adult
Biomarkers blood
Case-Control Studies
Humans
Linear Models
Male
Middle Aged
Multivariate Analysis
Statistics, Nonparametric
Surveys and Questionnaires
Environmental Pollutants blood
Lead blood
Occupational Exposure
Prolactin blood

Language :: English
ISSN :: 1366-5804
Volume :: 17
Issue :: 6
Database :: MEDLINE
Journal :: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals
Publication Type :: Academic Journal
Accession number :: 22642493
Full Text :: https://doi.org/10.3109/1354750X.2012.692391

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