Pulmonary metastatic giant cell tumors presenting as totally hyalinized and ossified nodules.

Authors :: Hsieh MS
Wu CT
Lin MW
Chang YL
Lee YC
Source :: The Annals of thoracic surgery [Ann Thorac Surg] 2012 Jun; Vol. 93 (6), pp. 2044-7.
Publication Year :: 2012
Abstract: We report a case of giant cell tumor of the left distal femur with simultaneous bilateral pulmonary metastases. Pathologic examination of the left lung nodule showed a metastatic giant cell tumor with a noncontinuous ossified rim, and the right lung nodules were totally hyalinized or ossified without residual giant cell tumor components. Hyalinization was a consistent finding in both the primary bone lesion and the pulmonary metastases. Because the patient did not receive chemotherapy or radiotherapy before her surgical procedure, we believe that these changes represent spontaneous tumor regression.<br /> (Copyright © 2012 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.)

Subjects :: Adult
Diagnosis, Differential
Female
Femoral Neoplasms diagnosis
Femoral Neoplasms pathology
Femur pathology
Follow-Up Studies
Giant Cell Tumor of Bone diagnosis
Giant Cell Tumor of Bone pathology
Humans
Lung pathology
Lung Neoplasms pathology
Multiple Pulmonary Nodules pathology
Neoplasm Recurrence, Local diagnosis
Neoplasm Recurrence, Local pathology
Neoplasm Recurrence, Local surgery
Neoplasm Regression, Spontaneous
Ossification, Heterotopic pathology
Pneumonectomy
Thoracic Surgery, Video-Assisted
Tomography, X-Ray Computed
Femoral Neoplasms surgery
Giant Cell Tumor of Bone secondary
Giant Cell Tumor of Bone surgery
Hyalin
Lung Neoplasms diagnosis
Lung Neoplasms secondary
Lung Neoplasms surgery
Multiple Pulmonary Nodules surgery
Ossification, Heterotopic diagnosis
Ossification, Heterotopic surgery

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