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Distribution of human papillomavirus types in Turkish women.
- Source :
-
European journal of gynaecological oncology [Eur J Gynaecol Oncol] 2012; Vol. 33 (2), pp. 204-6. - Publication Year :
- 2012
-
Abstract
- Purpose of Investigation: Since oncogenic types of human papillomavirus (HPV) are associated with a higher risk of cervical cancer and certain types can be controlled by a vaccine, a study has been performed to determine the HPV genotype distribution among Turkish women.<br />Methods: The study included patients with abnormal cytology or in the follow-up for cervical intraepithelial neoplasia between 2002 and 2009 at Hacettepe University Hospital. The results of 1797 consecutive cervical samples were analyzed retrospectively. INNO-LiPA HPV genotyping, HPV-Typing and Seeplex HPV 18-plex genotyping tests were used to determine the types of HPV.<br />Results: HPV was detected in 404 (22.4%) of 1797 samples studied. HPV DNA was identified in 194 cases by using HPV-Typing test but the specific genotype was not available. The most frequent genotype was HPV 16 which was observed in 103 cases (49.0%).<br />Conclusion: HPV 16 was the most common genotype observed among Turkish women with abnormal cytology. It suggests that HPV vaccination may be useful for prevention of cervical cancer in this population.
- Subjects :
- Adult
Coinfection
Female
Genotype
Human papillomavirus 16 genetics
Human papillomavirus 16 isolation & purification
Humans
Middle Aged
Papillomaviridae genetics
Prevalence
Retrospective Studies
Turkey epidemiology
DNA, Viral isolation & purification
Papillomaviridae isolation & purification
Papillomavirus Infections epidemiology
Papillomavirus Infections virology
Subjects
Details
- Language :
- English
- ISSN :
- 0392-2936
- Volume :
- 33
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- European journal of gynaecological oncology
- Publication Type :
- Academic Journal
- Accession number :
- 22611964