Diabetes differentially affects depression and self-rated health by age in the U.S.

Objective: To determine whether the relationship between age and physical and mental health varies by diabetes status in older U.S. adults.
Research Design and Methods: Using data from the National Social Life, Health, and Aging Project, a national sample of 3,005 adults aged 57-85 years, we tested the significance of the interaction between age and diabetes in association with health states.
Results: Respondents with diabetes in the youngest age cohort had more medical conditions than those without diabetes, a difference that narrowed with age (P for interaction <0.01). The youngest cohort with diabetes had a higher rate of depression compared to those without diabetes (14 vs. 8%). Depression declined with age and did not differ by diabetes status in the oldest respondents (P = 0.01 for age-diabetes interaction).
Conclusions: Diabetes differentially affects self-rated overall health and depression by age, with convergence in the oldest age-group with and without diabetes.