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Pausing on the path to robustness.
- Source :
-
Developmental cell [Dev Cell] 2012 May 15; Vol. 22 (5), pp. 905-6. - Publication Year :
- 2012
-
Abstract
- Heat-shock proteins (Hsps) maintain homeostasis by assisting protein folding, and the transcriptional regulation of Hsp-coding genes has long been under study. Sawarkar et al. (2012) now report in Cell that Hsp90 is itself a transcriptional regulator required for RNA polymerase pausing, contributing to rapid, robust induction of many genes.<br /> (Copyright © 2012 Elsevier Inc. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1878-1551
- Volume :
- 22
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Developmental cell
- Publication Type :
- Academic Journal
- Accession number :
- 22595664
- Full Text :
- https://doi.org/10.1016/j.devcel.2012.04.020